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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP3 subtype
Species	Mus musculus (Mouse)
Gene	Ptger3
Synonym	EP3 receptor PGE receptor EP3 subtype PGE2 receptor EP3 subtype prostaglandin E receptor 3 prostanoid EP3 receptor
Disease	N/A for non-human GPCRs
Length	365
Amino acid sequence	MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER
UniProt	P30557
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4336
IUPHAR	342
DrugBank	N/A

Ligand

Name	CHEMBL599419
Molecular formula	C28H29F2NO4
IUPAC name	3-[2-[[1-(3,4-difluorophenyl)-3-methylbutyl]carbamoyl]-4-(phenoxymethyl)phenyl]propanoic acid
Molecular weight	481.54
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.8
Synonyms	SCHEMBL2984353 3-[2-({[1-(3,4-Difluorophenyl)-3-methylbutyl]amino}-carbonyl)-4-(phenoxymethyl)phenyl]propanoic acid BDBM50307429
Inchi Key	HRIVQOQOXZBHSD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H29F2NO4/c1-18(2)14-26(21-10-12-24(29)25(30)16-21)31-28(34)23-15-19(8-9-20(23)11-13-27(32)33)17-35-22-6-4-3-5-7-22/h3-10,12,15-16,18,26H,11,13-14,17H2,1-2H3,(H,31,34)(H,32,33)
PubChem CID	23017440
ChEMBL	CHEMBL599419
IUPHAR	N/A
BindingDB	50307429
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	47.0 nM	PMID20129791	BindingDB,ChEMBL
Ki	0.4 nM	PMID20129791	BindingDB,ChEMBL

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