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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3641712
Molecular formula	C15H18N4O
IUPAC name	6-methyl-N-[4-[(2S)-morpholin-2-yl]phenyl]pyridazin-3-amine
Molecular weight	270.336
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	1.1
Synonyms	US8802673, 160 BDBM129518 SCHEMBL12610333
Inchi Key	HFUZOZOERXDHOL-CQSZACIVSA-N
Inchi ID	InChI=1S/C15H18N4O/c1-11-2-7-15(19-18-11)17-13-5-3-12(4-6-13)14-10-16-8-9-20-14/h2-7,14,16H,8-10H2,1H3,(H,17,19)/t14-/m1/s1
PubChem CID	68325862
ChEMBL	CHEMBL3641712
IUPHAR	N/A
BindingDB	129518
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	6.1 nM	, None	BindingDB,ChEMBL

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