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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3701924
Molecular formula	C18H19F3N2O2
IUPAC name	4-[(2S)-morpholin-2-yl]-N-[[4-(trifluoromethoxy)phenyl]methyl]aniline
Molecular weight	352.357
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.6
Synonyms	US8802673, 25 BDBM129383 SCHEMBL12609917
Inchi Key	HFQWIWDTZQPAMR-QGZVFWFLSA-N
Inchi ID	InChI=1S/C18H19F3N2O2/c19-18(20,21)25-16-7-1-13(2-8-16)11-23-15-5-3-14(4-6-15)17-12-22-9-10-24-17/h1-8,17,22-23H,9-12H2/t17-/m1/s1
PubChem CID	68325652
ChEMBL	CHEMBL3701924
IUPHAR	N/A
BindingDB	129383
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	12.4 nM	, None	BindingDB,ChEMBL

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