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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Rattus norvegicus (Rat)
Gene	Adora1
Synonym	A1 receptor A1-AR A1R adenosine receptor A1 RDC7
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
UniProt	P25099
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL318
IUPHAR	18
DrugBank	N/A

Ligand

Name	CHEMBL303883
Molecular formula	C15H17N5
IUPAC name	1-ethyl-4-pyrrolidin-1-yl-[1,2,4]triazolo[4,3-a]quinoxaline
Molecular weight	267.336
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.3
Synonyms	4-(1-Pyrrolidinyl)-1-ethyl[1,2,4]triazolo[4,3-a]quinoxaline ZINC7504173 BDBM50015826 1-ethyl-4-(pyrrolidin-1-yl)[1,2,4]triazolo[4,3-a]quinoxaline MCULE-4697289646 1-Ethyl-4-pyrrolidin-1-yl-[1,2,4]triazolo[4,3-a]quinoxaline STK919052 AKOS000482765 [ Show all ]
Inchi Key	APJHYJWRJHOAHR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H17N5/c1-2-13-17-18-15-14(19-9-5-6-10-19)16-11-7-3-4-8-12(11)20(13)15/h3-4,7-8H,2,5-6,9-10H2,1H3
PubChem CID	14783686
ChEMBL	CHEMBL303883
IUPHAR	N/A
BindingDB	50015826
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	10000.0 nM	PMID2374150	BindingDB,ChEMBL

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