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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin D2 receptor
Species	Mus musculus (Mouse)
Gene	Ptgdr
Synonym	prostanoid DP receptor-like Prostanoid DP receptor prostaglandin D2 receptor (DP) PGD2 receptor PGD receptor DP1 receptor DP1 PTGDR1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	357
Amino acid sequence	MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
UniProt	P70263
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3933
IUPHAR	338
DrugBank	N/A

Ligand

Name	CHEMBL365829
Molecular formula	C28H25NO5
IUPAC name	2-[1-[4-(3,4-dihydro-2H-chromen-2-ylmethoxy)benzoyl]-2-methylindol-4-yl]acetic acid
Molecular weight	455.51
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.5
Synonyms	{1-[4-(Chroman-2-ylmethoxy)-benzoyl]-2-methyl-1H-indol-4-yl}-acetic acid BDBM50152514 SCHEMBL5853087
Inchi Key	GWYIZWZVKYKMGF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H25NO5/c1-18-15-24-21(16-27(30)31)6-4-7-25(24)29(18)28(32)20-10-12-22(13-11-20)33-17-23-14-9-19-5-2-3-8-26(19)34-23/h2-8,10-13,15,23H,9,14,16-17H2,1H3,(H,30,31)
PubChem CID	21974374
ChEMBL	CHEMBL365829
IUPHAR	N/A
BindingDB	50152514
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	60.0 nM	PMID15341946	BindingDB,ChEMBL

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