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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Bos taurus (Bovine)
Gene	DRD2
Synonym	Dopamine D2 receptor
Disease	N/A for non-human GPCRs
Length	444
Amino acid sequence	MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
UniProt	P20288
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3998
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL341825
Molecular formula	C16H25N
IUPAC name	3-(2,3-dimethylphenyl)-1-propylpiperidine
Molecular weight	231.383
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	4.1
Synonyms	D0J8RP 3-(2,3-dimethylphenyl)-1-propylpiperidine 3-(2,3-Dimethyl-phenyl)-1-propyl-piperidine BDBM50068421
Inchi Key	AORDKZRSVBDZJZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H25N/c1-4-10-17-11-6-8-15(12-17)16-9-5-7-13(2)14(16)3/h5,7,9,15H,4,6,8,10-12H2,1-3H3
PubChem CID	10609576
ChEMBL	CHEMBL341825
IUPHAR	N/A
BindingDB	50068421
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	75.0 nM	PMID9836610	BindingDB
Ki	75.3 nM	PMID9836610	ChEMBL
Ki	4900.0 nM	PMID9836610	BindingDB,ChEMBL
Ki	7800.0 nM	PMID9836610	BindingDB,ChEMBL

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