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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melatonin receptor type 1C
Species	Gallus gallus (Chicken)
Gene
Synonym	CKB Mel-1C-R Mel1c receptor
Disease	N/A for non-human GPCRs
Length	346
Amino acid sequence	MERPGSNGSCSGCRLEGGPAARAASGLAAVLIVTIVVDVLGNALVILSVLRNKKLRNAGNIFVVSLSVADLVVAVYPYPLILSAIFHNGWTMGNIHCQISGFLMGLSVIGSIFNITAIAINRYCYICHSLRYDKLFNLKNTCCYICLTWTLTVVAIVPNFFVGSLQYDPRIYSCTFAQTVSTSYTITVVVVHFIVPLSIVTFCYLRIWILVIQVKHRVRQDCKQKIRAADIRNFLTMFVVFVLFAVCWGPLNFIGLAVSINPSKVQPHIPEWLFVLSYFMAYFNSCLNAVIYGLLNQNFRKEYKRILLMLRTPRLLFIDVSKGGTEGLKSKPSPAVTNNNQAEIHL
UniProt	P49288
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3196
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL33700
Molecular formula	C14H18N2O2
IUPAC name	N-[2-(5-methoxy-1-methylindol-3-yl)ethyl]acetamide
Molecular weight	246.31
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	1.5
Synonyms	N-(2-(5-methoxy-1-methyl-1H-indol-3-yl)ethyl)acetamide SCHEMBL5144427 N-[2-(1-Methyl-5-methoxy-1H-indole-3-yl)ethyl]acetamide ZINC13473193 BDBM50066960 methylmelatonin N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-acetamide [ Show all ]
Inchi Key	GSMWHFKFNGUYRN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H18N2O2/c1-10(17)15-7-6-11-9-16(2)14-5-4-12(18-3)8-13(11)14/h4-5,8-9H,6-7H2,1-3H3,(H,15,17)
PubChem CID	11776674
ChEMBL	CHEMBL33700
IUPHAR	N/A
BindingDB	50066960
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Relative affinity	11.0 -	PMID9748358	ChEMBL

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