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Structure of PDB 7znk Chain p

Receptor sequence >7znkp (length=367) Species: 9606 (Homo sapiens) [Search protein sequence] LKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAMGKTAVFVLATL QQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSI KKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQ LDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVKLT LHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLV EQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNI AFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFE VNISELPDEIDISSYIE

3D structure PDB 7znk mRNA recognition and packaging by the human transcription-export complex. Chain p Resolution 3.9 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number 3.6.4.13: RNA helicase.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 rna p T122 R123 G150 G151 T172 P173 G174 R175 D206 T68 R69 G96 G97 T118 P119 G120 R121 D152

Gene Ontology Molecular Function GO:0003676 nucleic acid binding GO:0003723 RNA binding GO:0003724 RNA helicase activity GO:0003729 mRNA binding GO:0004386 helicase activity GO:0005515 protein binding GO:0005524 ATP binding GO:0008186 ATP-dependent activity, acting on RNA GO:0016787 hydrolase activity GO:0016887 ATP hydrolysis activity GO:0017070 U6 snRNA binding GO:0030621 U4 snRNA binding GO:0042802 identical protein binding GO:0043008 ATP-dependent protein binding

	Biological Process
GO:0000245	spliceosomal complex assembly
GO:0000398	mRNA splicing, via spliceosome
GO:0006397	mRNA processing
GO:0006405	RNA export from nucleus
GO:0006406	mRNA export from nucleus
GO:0008380	RNA splicing
GO:0010501	RNA secondary structure unwinding
GO:0051028	mRNA transport

	Cellular Component
GO:0000346	transcription export complex
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005681	spliceosomal complex
GO:0005687	U4 snRNP
GO:0005688	U6 snRNP
GO:0005737	cytoplasm
GO:0016607	nuclear speck

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