Structure of PDB 5ui5 Chain V

Receptor sequence

>5ui5V (length=323) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence]

ELEELQQNIKLELEGKEQELALELLNYLNEKGFLSKSVEEISDVLRCSVE
ELEKVRQKVLRLEPLGVCSKDVWEFLELQIEEIYPEEEEILKKALRDLKR
GKKLKPEIKGKLSRLRLFPLSAEKVYTFAKVDAIIEEENGEFFIYLYEDF
IDIDLNEEYWELYKKSRNLQKELKEAFERYESIRKVLDIRRRNLRKVLEK
IVERQKDFLTGKGSLKPLTLREVSSEIGIHESTLSRIVNSKYVKTPVGTY
SLRTFFVRESAEGLTQGELMKLIKEIVENEDKRKPYSDQEIANILKEKGF
KVARRTVAKYREMLGIPSSRERR

3D structure

PDB

5ui5 Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme.

Chain

Resolution

3.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	V	T293 L294 R295 S309 R327 R332 D362 Q363 R378 R385 R394	T219 L220 R221 S235 R253 R258 D288 Q289 R304 R311 R320	PDBbind-CN: Kd=103nM
BS02	dna	V	S306 S334 R379 T380 Y384 R394	S232 S260 R305 T306 Y310 R320	PDBbind-CN: Kd=103nM

Gene Ontology

	Molecular Function
GO:0001216	DNA-binding transcription activator activity
GO:0003677	DNA binding
GO:0016987	sigma factor activity

	Biological Process
GO:0006352	DNA-templated transcription initiation

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Molecular Function

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Biological Process

External links

PDB	RCSB:5ui5, PDBe:5ui5, PDBj:5ui5
PDBsum	5ui5
PubMed	28223493
UniProt	O66858

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