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BioLiP

Structure of PDB 8wrb Chain R

Receptor sequence
>8wrbR (length=281) Species: 9606 (Homo sapiens) [Search protein sequence]
EKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIA
DLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFIS
LDRYIKINTTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHYR
DKHNAKGEAIFNFILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNS
GKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIVHKT
NEIMLVLSSFNSCLDPVMYFLMSSNIRKIMC
3D structure
PDB8wrb Structural basis for ligand recognition and signaling of the lysophosphatidylserine receptors GPR34 and GPR174
ChainR
Resolution2.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SER R Y135 F205 R286 Y289 N309 E310 Y86 F147 R228 Y231 N251 E252
BS02 UBL R A182 M189 F205 R208 N220 L223 M226 A124 M131 F147 R150 N162 L165 M168
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0045028 G protein-coupled purinergic nucleotide receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0035589 G protein-coupled purinergic nucleotide receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8wrb, PDBe:8wrb, PDBj:8wrb
PDBsum8wrb
PubMed38048360
UniProtQ9UPC5|GPR34_HUMAN Probable G-protein coupled receptor 34 (Gene Name=GPR34)

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