Structure of PDB 8ree Chain M

Receptor sequence

>8reeM (length=329) Species: 571 (Klebsiella oxytoca) [Search protein sequence]

AGTPSGNGVGETTQSLQDYLMWQVELTPFTDTDRAIATSIVDAVDDTGYL
TIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLS
QFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQ
SLDPRPGQSIQTGEPEYVIPDVLVRKVNDRWVVELNSDSLPSANDTLLRV
SRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSP
RGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLT
SMLSEQGIMVARRTVAKYRESLSIPPSNQ

3D structure

PDB

8ree Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.

Chain

Resolution

3.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	M	L367 S382 R383 K400 S405 S438 D439 P469	L224 S239 R240 K257 S262 S295 D296 P326
BS02	dna	M	M376 H377 H406 V407 A454 R456 T457	M233 H234 H263 V264 A311 R313 T314

Gene Ontology

	Molecular Function
GO:0001216	DNA-binding transcription activator activity
GO:0016987	sigma factor activity

View graph for
Molecular Function

External links

PDB	RCSB:8ree, PDBe:8ree, PDBj:8ree
PDBsum	8ree
PubMed	38170755
UniProt	P06223\|RP54_KLEOX RNA polymerase sigma-54 factor (Gene Name=rpoN)

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