Structure of PDB 8xfy Chain I

Receptor sequence

>8xfyI (length=260) Species: 9606 (Homo sapiens) [Search protein sequence]

ADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKDILVEVNHP
FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELA
LALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEFCGTVEYMAPE
VVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMP
QFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRR
EIHPPFKPAT

3D structure

PDB

8xfy The Crystal Structure of RSK2 from Biortus.

Chain

Resolution

3.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.11.1: non-specific serine/threonine protein kinase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	A1LU8	I	Q76 F79 K100 D148 F149 L150 L200 T210 D211 F212	Q14 F17 K38 D70 F71 L72 L122 T132 D133 F134

Gene Ontology

	Molecular Function
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0005524	ATP binding

	Biological Process
GO:0006468	protein phosphorylation

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:8xfy, PDBe:8xfy, PDBj:8xfy
PDBsum	8xfy
PubMed
UniProt	P51812\|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 (Gene Name=RPS6KA3)

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