Structure of PDB 4k6t Chain G

Receptor sequence

>4k6tG (length=185) Species: 52275 (Human adenovirus D37) [Search protein sequence]

YDTRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKY
HIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAY
EKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQE
TGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE

3D structure

PDB

4k6t Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.

Chain

Resolution

2.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	SIA	G	Y308 V322	Y128 V142
BS02	SIA	G	Y312 P317 D318 K345	Y132 P137 D138 K165
BS03	CA	G	K212 E365	K32 E185

Gene Ontology

	Biological Process
GO:0007155	cell adhesion
GO:0019058	viral life cycle
GO:0019062	virion attachment to host cell

	Cellular Component
GO:0019028	viral capsid

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:4k6t, PDBe:4k6t, PDBj:4k6t
PDBsum	4k6t
PubMed	26177934
UniProt	Q64823

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