Structure of PDB 1ahj Chain G

Receptor sequence

>1ahjG (length=198) Species: 76275 (Rhodococcus sp. R312) [Search protein sequence]

ENAAPAQAAVSDRAWALFRALDGKGLVPDGYVEGWKKTFEEDFSPRRGAE
LVARAWTDPEFRQLLLTDGTAAVAQYGYLGPQGEYIVAVEDTPTLKNVIV
CSLCSCTAWPILGLPPTWYKSFEYRARVVREPRKVLSEMGTEIASDIEIR
VYDTTAETRYMVLPQRPAGTEGWSQEQLQEIVTKDCLIGVAIPQVPTV

3D structure

PDB

1ahj Crystal structure of nitrile hydratase reveals a novel iron centre in a novel fold.

Chain

Resolution

2.65 Å

3D
structure

Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Catalytic site (original residue number in PDB)	C110 C113 S114 C115
Catalytic site (residue number reindexed from 1)	C101 C104 S105 C106
Enzyme Commision number	4.2.1.84: nitrile hydratase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FE	G	C110 C113 S114 C115	C101 C104 S105 C106

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0016829	lyase activity
GO:0018822	nitrile hydratase activity
GO:0046872	metal ion binding
GO:0046914	transition metal ion binding
GO:0080109	indole-3-acetonitrile nitrile hydratase activity

View graph for
Molecular Function

External links

PDB	RCSB:1ahj, PDBe:1ahj, PDBj:1ahj
PDBsum	1ahj
PubMed	9195885
UniProt	P13448\|NHAA_RHOER Nitrile hydratase subunit alpha (Gene Name=nthA)

[Back to BioLiP]

zhanglab

zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417