BioLiP

Structure of PDB 3qzw Chain D

Receptor sequence

>3qzwD (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFG
CDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAA
HVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW

3D structure

PDB

3qzw Plasticity of human CD8alpha alpha binding to peptide-HLA-A*2402

Chain

Resolution

2.798 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	D	Y7 E63 K66 V67 H70 N77 Y84 M97 F99 H114 Y116 Y123 T143 K146 W147 Q156 Y159 R170 Y171	Y7 E63 K66 V67 H70 N77 Y84 M97 F99 H114 Y116 Y123 T143 K146 W147 Q156 Y159 R170 Y171

External links

PDB	RCSB:3qzw, PDBe:3qzw, PDBj:3qzw
PDBsum	3qzw
PubMed	21645925
UniProt	P04439\|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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