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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

Structure of PDB 7mzc Chain C

Receptor sequence >7mzcC (length=528) Species: 10116 (Rattus norvegicus) [Search protein sequence] QTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELP LSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDN TKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAY ILQREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAY SSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAA AYYRPVEGLPPYKLKNTVGDYFRVTGEILSVSGGVYFFFRGIQYFLQRRP SLKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRKEYVASMVFSLAMGWTN MLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLIED GKYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILL LNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKAFRSGK LLQVGFTPDGKDDYRWCFRVDEVNWTTW

3D structure PDB 7mzc Structural snapshots of TRPV1 reveal mechanism of polymodal functionality. Chain C Resolution 3.03 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number ?

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 6EU C F587 L669 F386 L445 BindingDB: Ki=0.13nM,IC50=180nM BS02 6EU C Y511 S512 L515 M547 T550 N551 Y554 Y310 S311 L314 M346 T349 N350 Y353 BindingDB: Ki=0.13nM,IC50=180nM

Gene Ontology Molecular Function GO:0005216 monoatomic ion channel activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0055085	transmembrane transport

	Cellular Component
GO:0016020	membrane

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