Structure of PDB 8c1l Chain B

Receptor sequence

>8c1lB (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]

PSINALLQAEVLSRDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCE
LPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAE
MSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKR
LRSQVQVSLEDYINDRYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLF
GMAKIDNLLQEMLLGG

3D structure

PDB

8c1l Crystal structure of HNF4 alpha LBD in complexes with palmitic acid and GRIP-1 peptide

Chain

Resolution

2.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	K194 F199 L204 R212 N359 E363	K43 F48 L53 R61 N207 E211

External links

PDB	RCSB:8c1l, PDBe:8c1l, PDBj:8c1l
PDBsum	8c1l
PubMed
UniProt	P41235\|HNF4A_HUMAN Hepatocyte nuclear factor 4-alpha (Gene Name=HNF4A)

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