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Structure of PDB 7qbi Chain B

Receptor sequence >7qbiB (length=298) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] APSLSNLFYDPTYNPGQSTINYTSIYGNGSTITFDELQGLVNSTVTQAIM FGVRCGAAALTLIVMWMTSRSRKTPIFIINQVSLFLIILHSALYFKYLLS NYSSVTYALTGFPQFISRGDVHVYGATNIIQVLLVASIETSLVFQIKVIF TGDNFKRIGLMLTSISFTLGIATVTMYFVSAVKGMIVTYNDVSATQDKYF NASTILLASSINFMSFVLVVKLILAIRSRRFLGLKQFDSFHILLIMSCQS LLVPSIIFILAYSLKPNQGTDVLTTVATLLAVLSLPLSSMWATAANNA

3D structure PDB 7qbi Activation mechanism of the class D fungal GPCR dimer Ste2. Chain B Resolution 3.46 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number ?

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 peptide B Q51 H94 Y101 Y128 T131 N132 Q135 Y181 A198 D201 F204 N205 Y266 L268 D275 V276 T279 Q47 H90 Y97 Y124 T127 N128 Q131 Y177 A194 D197 F200 N201 Y262 L264 D271 V272 T275 BS02 Y01 B A206 I209 A202 I205 BS03 Y01 B A63 L103 A59 L99 BS04 Y01 B N46 T50 M54 N42 T46 M50 BS05 Y01 B L93 K100 G123 L89 K96 G119

Gene Ontology Molecular Function GO:0004930 G protein-coupled receptor activity GO:0004932 mating-type factor pheromone receptor activity GO:0004934 mating-type alpha-factor pheromone receptor activity GO:0005515 protein binding

	Biological Process
GO:0000750	pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0000755	cytogamy
GO:0007186	G protein-coupled receptor signaling pathway
GO:0019236	response to pheromone

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0038038	G protein-coupled receptor homodimeric complex

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