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Structure of PDB 5k27 Chain B

Receptor sequence >5k27B (length=449) Species: 32630 (synthetic construct) [Search protein sequence] MEDIKKISIFLAYNVNVDAIKYLKEEDIQKLIEEFGEEEIIEKIEEYPRK IKEPLDFVARLIHAIKTGKPAEVPLDNEELNKWFDSLFKYDEERMGGQVG IIANLLAILDLKKVIAYSPLLSKKQAEMFNNDLLYPIVENGKLVLKKPIE AYKDNDPIKINRIFEFKEGIKFKLGDEKIIAPQANRFIVASRPLARIEIK EDLKKYLPEIGEMVDCAILSGYQGIKEKYSDGKTAEYYFKRAKEDIKLLK KKDIKVHLEFASIQNIKIRKKVVDYILPNVDSVGMDETEIANILNILGYE ELSEKILKDSKIEDVIEGAKILLDKFNLEVVQVHTIYYILFISKKDNPLS KEELKKTLEFATILAATKAKLGDIKNIEDLKVGLKVPHNKYGELLKEIVE KLKKKKKKEDYKIVLIPSRFVENPKSTVGLGDTISTGAFVSYVSLLKKK

3D structure PDB 5k27 Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases. Chain B Resolution 2.58 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 AMP B T337 I338 F422 V423 G431 L432 G433 I436 T335 I336 F420 V421 G429 L430 G431 I434

Gene Ontology --> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Tue May 20 11:53:26 2025

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

/var/www/html/BioLiP2/pdb.cgi in <module>()

1709                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

1710         else:

=> 1711             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

1712

1713     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '5k27', asym_id = 'B', title = 'Reconstructed ancestral enzymes reveal that nega... substrate specificity in ADP-dependent kinases. '

/var/www/html/BioLiP2/pdb.cgi in display_protein_receptor(pdbid='5k27', asym_id='B', title='Reconstructed ancestral enzymes reveal that nega... substrate specificity in ADP-dependent kinases. ')

843

844     if go:

=>  845         display_go(go,uniprot,pdbid,asym_id)

846     return pubmed,uniprot

847

global display_go = <function display_go>, go = '0000287,0005737,0005975,0006000,0006096,0008443,0016773', uniprot = '', pdbid = '5k27', asym_id = 'B'

/var/www/html/BioLiP2/pdb.cgi in display_go(go='0000287,0005737,0005975,0006000,0006096,0008443,0016773', uniprot='', pdbid='5k27', asym_id='B')

484         '''.replace("$namespace_link",namespace_link

485           ).replace("$namespace",namespace

=>  486           ).replace("$uniprot",u

487         ))

488         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>