Structure of PDB 4io5 Chain B

Receptor sequence

>4io5B (length=242) Species: 104782 (Adineta vaga) [Search protein sequence]

GSARLKGITLRIGVIESVPFTIVANVITTKLTGYVLDLIEYLRDKMGFVA
DVQLAPPNTSYTGLVLALANGDYDIAIGDITVTSARREIVAFSNSISDNS
MRILMRKGTLIDGMDDLKNGKIPYNRIGIRIGTAGEDYYLREISGGSRNF
YPLKSRQEMYDSLLAGIIDVSFMDIGTAEYVTNNIYCNLTLVGEDFDKST
FGIVTPKEWLYAKDLDVNILSLRETGILDNLKKKWFQTKACP

3D structure

PDB

4io5 Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.

Chain

Resolution

1.721 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ALA	B	Y67 I86 T87 R92 T139 D180	Y61 I80 T81 R86 T133 D174	MOAD: Kd=9uM
BS02	CL	B	R93 K213	R87 K207
BS03	CL	B	R136 D180	R130 D174

Gene Ontology

	Molecular Function
GO:0015276	ligand-gated monoatomic ion channel activity

	Cellular Component
GO:0016020	membrane

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Molecular Function

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Cellular Component

External links

PDB	RCSB:4io5, PDBe:4io5, PDBj:4io5
PDBsum	4io5
PubMed	23434404
UniProt	E9P5T5

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