BioLiP

Structure of PDB 1z1g Chain B

Receptor sequence

>1z1gB (length=336) Species: 10710 (Lambdavirus lambda) [Search protein sequence]

RDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELFSGH
KHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRR
GLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAEGH
ITTNHVAATRAAKSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVT
GQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTALHIDALGISMKETL
DKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSFEGDPPTFHE
LRSLSARLYEKQISDKFAQHLLGHKSDTEWDKIEIK

3D structure

PDB

1z1g A structural basis for allosteric control of DNA recombination by lambda integrase.

Chain

Resolution

4.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.7.-
3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	K136 V175 R176 R177 R212 K235 R276 S281 H308	K127 V166 R167 R168 R203 K226 R267 S272 H299
BS02	dna	B	I92 K93 N99 R152 G214 S234 K235 R287 M290 R293 T306 F307 H308	I83 K84 N90 R143 G205 S225 K226 R278 M281 R284 T297 F298 H299
BS03	dna	B	R19 Y23 K33 E34 F35 G36 R39	R10 Y14 K24 E25 F26 G27 R30
BS04	dna	B	R10 P14 N15 Y17	R1 P5 N6 Y8

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0008907	integrase activity
GO:0016740	transferase activity
GO:0016787	hydrolase activity

	Biological Process
GO:0006310	DNA recombination
GO:0015074	DNA integration
GO:0032359	provirus excision
GO:0044826	viral genome integration into host DNA
GO:0046718	symbiont entry into host cell
GO:0075713	establishment of integrated proviral latency

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Molecular Function

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Biological Process

PDB	RCSB:1z1g, PDBe:1z1g, PDBj:1z1g
PDBsum	1z1g
PubMed	15973401
UniProt	P03700\|VINT_LAMBD Integrase (Gene Name=int)