Structure of PDB 1soz Chain B

Receptor sequence

>1sozB (length=281) Species: 562 (Escherichia coli) [Search protein sequence]

MTPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYI
ITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTI
PINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQ
TDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLA
TKIMDKLIRDGRVIRGYIGIGGRIVVNEGPAANAGIQVNDLIISVDNKPA
ISALETMDQVAEIRPGSVIPVLQVTIQEYPA

3D structure

PDB

1soz Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease

Chain

Resolution

2.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

3.4.21.107: peptidase Do.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	I261 G262 G263 R264 V283 N285 A315 T318 M319	I220 G221 G222 R223 V225 N227 A253 T256 M257

Gene Ontology

	Molecular Function
GO:0004252	serine-type endopeptidase activity

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:1soz, PDBe:1soz, PDBj:1soz
PDBsum	1soz
PubMed	15137941
UniProt	P0AEE3\|DEGS_ECOLI Serine endoprotease DegS (Gene Name=degS)

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