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Structure of PDB 1efa Chain B

Receptor sequence >1efaB (length=330) Species: 562 (Escherichia coli) [Search protein sequence] KPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPNR VAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVER SGVEACKTAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVS DQTPINSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGW HKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMAL GAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSV DRLLQLSQGQAVKGNQLLPVSLVKRKTTLA

3D structure PDB 1efa A closer view of the conformation of the Lac repressor bound to operator. Chain B Resolution 2.6 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number ?

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 dna B L6 Q18 S21 N25 Y47 A53 Q54 A57 L5 Q17 S20 N24 Y46 A52 Q53 A56 BS02 dna B V15 S16 Y17 T19 R22 H29 V30 S31 T34 L56 A57 V14 S15 Y16 T18 R21 H28 V29 S30 T33 L55 A56 BS03 NPF B A75 D149 F161 S193 R197 W220 N246 D274 F293 A74 D148 F160 S192 R196 W219 N245 D273 F292

Gene Ontology Molecular Function GO:0000976 transcription cis-regulatory region binding GO:0000987 cis-regulatory region sequence-specific DNA binding GO:0001217 DNA-binding transcription repressor activity GO:0003677 DNA binding GO:0003700 DNA-binding transcription factor activity GO:0042802 identical protein binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0045892	negative regulation of DNA-templated transcription

	Cellular Component
GO:0005829	cytosol

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