BioLiP

Structure of PDB 8wrj Chain A

Receptor sequence

>8wrjA (length=429) Species: 4058 (Catharanthus roseus) [Search protein sequence]

PIHILAFPFPAKGHINPLLHLCNRLASKGFKITLITTVSTLKSVKTSKAN
GIDIESIPDGIPQIITVMEMNMELYFKQFKASAIENTTKLIQKLKTKNPL
PKVLIYDSSMPWILEVAHEQGLLGASFFTQPCSVSAIYYHMLQGTIKLPM
VSLPYLPLLEIKDLPGVQQFEDNSEAVAELLADQFSNIDDVDYVLFNTFD
ALEIEVVNWMGSKWPILTVGPTAPTSINYLFETNTEVCMKWLDQREIDTV
IYVSFGSLASLTEEQMEQVSQALIRSNCYFLWVVREEEENKLPKDFKETT
SKKKGLVINWCPQLDVLAHKSVACFMTHCGWNSTLEALCSGVPMICMPQW
ADQTTNAKLIEHVWKIGVGVNKSIVKREEIEDCIRQVIESERGKELKRNA
IKWKELAKEAVSEGGSSCNNIQEFSSSLL

3D structure

PDB

8wrj Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3

Chain

Resolution

1.85 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.4.1.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	6JI	A	F11 I72 E76 M79 S116 F184 L194 L195 Q198	F9 I65 E69 M72 S109 F170 L180 L181 Q184
BS02	UDP	A	G15 N18 S287 V313 W340 C341 Q343 H358 G360 N362 S363 E366	G13 N16 S257 V283 W310 C311 Q313 H328 G330 N332 S333 E336

Gene Ontology

	Molecular Function
GO:0008194	UDP-glycosyltransferase activity
GO:0016757	glycosyltransferase activity
GO:0080043	quercetin 3-O-glucosyltransferase activity
GO:0080044	quercetin 7-O-glucosyltransferase activity

View graph for
Molecular Function

PDB	RCSB:8wrj, PDBe:8wrj, PDBj:8wrj
PDBsum	8wrj
PubMed
UniProt	W8JMV4\|UGT9_CATRO UDP glycosyltransferase 9 (Gene Name=UGT9)