Structure of PDB 8t59 Chain A

Receptor sequence

>8t59A (length=210) Species: 32630 (synthetic construct) [Search protein sequence]

EVQLVESGGGLVQPGGSLKLSCATSGFPFSNVWLHWVRQASGKGPEWVAH
IKAKSDNYATYYAESVKGRFTISRDDSKNTVYLQMNSLKTEDTAVYYCTD
ILEYWGQGTLVTVSSASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTV
SWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKP
SNTKVDKKVE

3D structure

PDB

8t59 Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining

Chain

Resolution

2.0 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	F27 P28 V32 W33 D100 L102 E103 Y104	F27 P28 V32 W33 D100 L102 E103 Y104

External links

PDB	RCSB:8t59, PDBe:8t59, PDBj:8t59
PDBsum	8t59
PubMed

[Back to BioLiP]

zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417