Structure of PDB 8pdn Chain A

Receptor sequence

>8pdnA (length=339) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence]

DLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGEILYAKHADY
KYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSQMLDIHGVEK
SWVEEIDKEARKTMATLLKESSGNIPQNQRPSAPDTPIILLCVGALIFTK
LASTIEVGLETTVRRANRVLSDALKRYPRMDIPKIARSFYDLFEQKVYHR
SLFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTMLRWGVIARSSNNI
MLGHVSVQAELKQVTEVYDLVREMGPESGLLHLRQSPKAGLLSLANCPNF
ASVVLGNASGLGIIGMYRGRVPNTELFSAAESYAKSLKE

3D structure

PDB

8pdn Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.

Chain

Resolution

4.7 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A	K171 A173 S174 R185 R186 R189 Q250 G255 T257 W261 S314 I334 M337 Y338 R339	K150 A152 S153 R164 R165 R168 Q229 G234 T236 W240 S293 I313 M316 Y317 R318
BS02	rna	A	R186 R189 V190 S242 L243 N246	R165 R168 V169 S221 L222 N225

Gene Ontology

	Molecular Function
GO:0003723	RNA binding

	Cellular Component
GO:0019013	viral nucleocapsid
GO:0019029	helical viral capsid
GO:0030430	host cell cytoplasm
GO:1990904	ribonucleoprotein complex

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Molecular Function

View graph for
Cellular Component

External links

PDB	RCSB:8pdn, PDBe:8pdn, PDBj:8pdn
PDBsum	8pdn
PubMed	37993464
UniProt	Q6WBA1\|NCAP_HMPVC Nucleoprotein (Gene Name=N)

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