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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

Structure of PDB 8ed8 Chain A

Receptor sequence >8ed8A (length=968) Species: 10090 (Mus musculus) [Search protein sequence] ISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQ LELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTG VIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMS NPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRI GQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGH KYSEVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDL AILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAM LDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVR DVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLNHFP FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASEN DMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNA TCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPP SILSLEFKNGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWP STQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAI LLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVM MIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPY WMIYGEVFADQIDPPCQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAV FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHV CRDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSE RVENMSMRLEEVNEREHS

3D structure PDB 8ed8 Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Chain A Resolution 3.2 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number ?

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 peptide A T133 Q134 S136 P137 T138 F141 S161 D298 N299 T5 Q6 S8 P9 T10 F13 S33 D170 N171 BS02 9Z9 A P1038 S1039 W1040 P787 S788 W789 BS03 PIO A S773 L775 W876 I989 F990 N993 K994 S588 L590 W625 I738 F739 N742 K743

Gene Ontology Molecular Function GO:0005216 monoatomic ion channel activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0051262	protein tetramerization
GO:0055085	transmembrane transport

	Cellular Component
GO:0016020	membrane

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