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Structure of PDB 7u1p Chain A

Receptor sequence >7u1pA (length=617) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] SFPEGKPNCLLGLTIVFTGVLPTLERGASEALAKRYGARVTKSISSKTSV VVLGDEAGPKKLEKIKQLKIKAIDEEGFKQLIAGMPAEGDGEAAEKARRK LEEQHNIATKEAELLVKKEEERSKKLAAVVREEDKLWTVKYAPTNLQQVC GNKGSVMKLKNWLANWENSKKNSFKHAGKDGSGVFRAAMLYGPPGIGKTT AAHLVAQELGYDILEQNASDVRSKTLLNAGVKNALDNMSVVGYFKHNEEA QNLNGKHFVIIMDEVDGMSGGDRGGVGQLAQFCRKTSTPLILICNERNLP KMRPFDRVCLDIQFRRPDANSIKSRLMTIAIREKFKLDPNVIDRLIQTTR GDIRQVINLLSTISTTTKTINHENINEISKAWEKNIALKPFDIAHKMLDG QIYSDIGSRNFTLNDKIALYFDDFDFTPLMIQENYLSTRPSVLKPGQSHL EAVAEAANCISLGDIVEKKIRSSEQLWSLLPLHAVLSSVYPASKVAGHMA GRINFTAWLGQNSKSAKYYRLLQEIHYHTRLGTSTDKIGLRLDYLPTFRK RLLDPFLKQGADAISSVIEVMDDYYLTKEDWDSIMEFFVGPDVTTAIIKK IPATVKSGFTRKYNSMT

3D structure PDB 7u1p A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA. Chain A Resolution 3.0 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number ?

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 dna A R434 F582 W638 P642 R273 F421 W477 P481 BS02 dna A T189 S193 S194 K195 R383 S384 K385 T386 N459 Q474 R476 R477 P551 F552 F587 R632 S633 S634 Q636 W638 F666 L670 T41 S45 S46 K47 R222 S223 K224 T225 N298 Q313 R315 R316 P390 F391 F426 R471 S472 S473 Q475 W477 F505 L509 BS03 dna A K195 G315 R476 H556 M660 G662 R663 I664 K47 G154 R315 H395 M499 G501 R502 I503 BS04 AGS A T299 A303 P304 C311 G356 I357 G358 K359 T360 N456 I514 R515 T138 A142 P143 C150 G195 I196 G197 K198 T199 N295 I353 R354

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003689 DNA clamp loader activity GO:0005515 protein binding GO:0005524 ATP binding GO:0016887 ATP hydrolysis activity

	Biological Process
GO:0000278	mitotic cell cycle
GO:0006260	DNA replication
GO:0006261	DNA-templated DNA replication
GO:0006271	DNA strand elongation involved in DNA replication
GO:0006272	leading strand elongation
GO:0006281	DNA repair
GO:0006298	mismatch repair
GO:0051301	cell division

	Cellular Component
GO:0005634	nucleus
GO:0005663	DNA replication factor C complex

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