Structure of PDB 7t8y Chain A

Receptor sequence

>7t8yA (length=158) Species: 1314 (Streptococcus pyogenes) [Search protein sequence]

LPVIGGIAIPELGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLAS
HHIFGITGSSQMLFSPLERAQNGMSIYLTDKEKIYEYIIKDVFTVAPERV
DVIDDTAGLKEVTLVTCTDIEATERIIVKGELKTEYDFDKAPADVLKAFN
HSYNQVST

3D structure

PDB

7t8y Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.

Chain

Resolution

1.8 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	M125 S141 H142 H143 I144 P188 R190 V191 T207 C208 I211 R216	M34 S50 H51 H52 I53 P97 R99 V100 T116 C117 I120 R125
BS02	peptide	A	T116 Y120 T249	T25 Y29 T158

External links

PDB	RCSB:7t8y, PDBe:7t8y, PDBj:7t8y
PDBsum	7t8y
PubMed	36055407
UniProt	Q99ZN4

[Back to BioLiP]

zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417