BioLiP

Structure of PDB 6p0g Chain A

Receptor sequence

>6p0gA (length=173) Species: 593117 (Thermococcus gammatolerans EJ3) [Search protein sequence]

NQLFIIGIGTGTDEYENFEETILKGVKRNELEGQIGPDILDNCCSDVCYF
WGRSKETIYEKKIDKGDMVLFYVGKRISRNKVDLNQETAVYLGIICETVE
ISENDVSFLNDFWRKGENFRFLMFFKKKPEKLHHSINEINSKLGYNPDYF
PIAGYVKPERMSGVYDILKNILK

3D structure

PDB

6p0g The structure of theThermococcus gammatoleransMcrB N-terminal domain reveals a new mode of substrate recognition and specificity among McrB homologs.

Chain

Resolution

2.27 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	N19 W53 G54 R55 R81 F121 I154	N17 W51 G52 R53 R79 F119 I152	PDBbind-CN: Kd=0.707uM
BS02	dna	A	Y61 N82 K83 Y147 N148 Y151 Y157 K159 R162	Y59 N80 K81 Y145 N146 Y149 Y155 K157 R160	PDBbind-CN: Kd=0.707uM

External links

PDB	RCSB:6p0g, PDBe:6p0g, PDBj:6p0g
PDBsum	6p0g
PubMed	31822563
UniProt	C5A3Z3

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