Structure of PDB 4z0e Chain A

Receptor sequence

>4z0eA (length=270) Species: 1036723 (Plasmodium falciparum Vietnam Oak-Knoll (FVO)) [Search protein sequence]

NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVGTQYRLPSGKCPVFGKGIII
ETTFLKPVAKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLC
SRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNGFCFRPAKDK
LFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSAN
DLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTC
LINNSSYIATTALSHPIEVE

3D structure

PDB

4z0e Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.

Chain

Resolution

1.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	F183 T186 G222 N223 M224 N225 P226 N228 S232 Y234 Y236	F66 T69 G105 N106 M107 N108 P109 N111 S114 Y116 Y118

Gene Ontology

	Cellular Component
GO:0016020	membrane

View graph for
Cellular Component

External links

PDB	RCSB:4z0e, PDBe:4z0e, PDBj:4z0e
PDBsum	4z0e
PubMed	27422009
UniProt	A0A024UZE1

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