Structure of PDB 4jno Chain A

Receptor sequence

>4jnoA (length=586) Species: 5833 (Plasmodium falciparum) [Search protein sequence]

RTHLFACGIKRKSIKWICRENSEKITVCVPDRKIQLCIANFLNSRLETME
KFKEIFLISVNTEAKLLYNKNEGKDPSIFCNELRNSFSDFRNSFIGDDMD
FGGNTDRVKGYINKKFSDYYKEKNVEKLNNIKKEWWEKNKANLWNHMIVN
HKGNIAKECAIIPAEEPQINLWIKEWNENFLMEKKRLFLNIKDKCVENKK
YEACFGGCRLPCSSYTSFMKKSKTQMEVLTNLYKKKNSGVDKNNFLNDLF
KKNNKNDLDDFFKNEKEYDDLCDCRYTATIIKSFLNGPAKNDVDIASQIN
VNDLRGFGCNYKSNNEKSWNCAGTFTNKFPGTCEPPRRQTLCLGRTYLLH
RGHEEDYKEHLLGASIYEAQLLKYKYKEKDENALCSIIQNSYADLADIIK
GSDIIKDYYGKKMEENLNKVNKDKKRNEESLKIFREKWWDENKENVWKVM
SAVLKNKETCKDYDKFQKIPQFLRWFKEWGDDFCEKRKEKIYSFESFKVE
CKKKTCKNKCSEYKKWIDLKKSEYEKQVDKYTKDKNKKMYDNIDEVKEAN
VYLKEKSKECKDVNFDDKIFNEAPNEYEDMCKKCDE

3D structure

PDB

4jno Molecular Basis for Sialic Acid-dependent Receptor Recognition by the Plasmodium falciparum Invasion Protein Erythrocyte-binding Antigen-140/BAEBL.

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	SIA	A	C456 N457 K464 Q486 T487 L488	C309 N310 K317 Q339 T340 L341
BS02	SIA	A	C154 G155 Q182 G250 N251	C7 G8 Q35 G103 N104

Gene Ontology

	Molecular Function
GO:0046789	host cell surface receptor binding

	Cellular Component
GO:0016020	membrane

View graph for
Molecular Function

View graph for
Cellular Component

External links

PDB	RCSB:4jno, PDBe:4jno, PDBj:4jno
PDBsum	4jno
PubMed	23508963
UniProt	Q8WS31

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