Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

Structure of PDB 3x0q Chain A

Receptor sequence >3x0qA (length=154) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] ERTYLYRGRILNLALEGRYEIVEHKPAVAVIALREGRMLFVRQMRPAVGL APLEIPAGLIEPGEDPLEAARRELAEETGLSGDLTYLFSYFVSPGFTDEK THVFLAENLKEVEAEAIEVVWMRPEEALERHQRGEVEFSATGLVGVLYYH AFLR

3D structure PDB 3x0q ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors Chain A Resolution 1.14 Å 3D structure Catalytic site residues are labeled in the structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Catalytic site (original residue number in PDB) R54 A66 E82 E86 Catalytic site (residue number reindexed from 1) R45 A57 E73 E77 Enzyme Commision number 3.6.1.13: ADP-ribose diphosphatase.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 AR6 A I19 R54 A66 G67 E82 E108 I10 R45 A57 G58 E73 E99 BS02 MN A A66 E86 A57 E77 BS03 MN A E82 E86 E73 E77 BS04 MN A E129 I131 E115 I117

Gene Ontology Molecular Function GO:0016462 pyrophosphatase activity GO:0016787 hydrolase activity GO:0046872 metal ion binding

	Biological Process
GO:0006753	nucleoside phosphate metabolic process
GO:0019693	ribose phosphate metabolic process

	Cellular Component
GO:0005829	cytosol

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component