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Structure of PDB 3k9f Chain A

Receptor sequence >3k9fA (length=481) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence] NIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDS NTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEP TVLPAAFPNLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKID KLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKE QIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIEL KKDANTELVLNYLFKYTDLQINYNFNMVAIDNFTPRQVGIVPILSSYIAH RREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAK ENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAI IGDERTMYNLMKKELREVKKKFATPRLSSLE

3D structure PDB 3k9f Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases Chain A Resolution 2.9 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 dna A R28 K38 V40 H74 H76 R87 K93 E262 R26 K36 V38 H72 H74 R85 K91 E260 BS02 dna A Y118 I170 S171 G173 Y174 N326 Y116 I168 S169 G171 Y172 N324

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity GO:0005524 ATP binding

	Biological Process
GO:0006259	DNA metabolic process
GO:0006265	DNA topological change

	Cellular Component
GO:0005694	chromosome

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