BioLiP

Structure of PDB 3ecb Chain A

Receptor sequence

>3ecbA (length=273) Species: 10090 (Mus musculus) [Search protein sequence]

SHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARW
IEQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAGC
DVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAG
AAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTL
RCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPL
GKEQKYTCHVEHEGLPEPLTLRW

3D structure

PDB

3ecb Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position

Chain

Resolution

1.698 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Y7 E63 R66 N70 F74 D77 Y84 W114 T143 K146 W147 Y159 E163 W167 Y171	Y6 E62 R65 N69 F73 D76 Y83 W113 T142 K145 W146 Y158 E162 W166 Y170

External links

PDB	RCSB:3ecb, PDBe:3ecb, PDBj:3ecb
PDBsum	3ecb
PubMed	19625641
UniProt	P01900\|HA12_MOUSE H-2 class I histocompatibility antigen, D-D alpha chain (Gene Name=H2-D1)

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