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Structure of PDB 3d0a Chain A

Receptor sequence >3d0aA (length=196) Species: 9606 (Homo sapiens) [Search protein sequence] SVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQL WVDSTPPPGTRVRAMAIYKQSQRMTEVVRRCPHHERCSDSDGLAPPQHLI RVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGG MNRSPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRK

3D structure PDB 3d0a Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations Chain A Resolution 1.8 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number ?

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 dna A A119 K120 S121 A24 K25 S26 BS02 dna A S241 R248 R273 C275 A276 R280 S146 R153 R178 C180 A181 R185 BS03 ZN A C176 H179 C238 C242 C81 H84 C143 C147

Gene Ontology Molecular Function GO:0000976 transcription cis-regulatory region binding GO:0003677 DNA binding GO:0003700 DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0006915	apoptotic process

	Cellular Component
GO:0005634	nucleus

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