Structure of PDB 2i32 Chain A

Receptor sequence

>2i32A (length=154) Species: 9606 (Homo sapiens) [Search protein sequence]

MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAES
EEYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCT
YRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFH
INWE

3D structure

PDB

2i32 Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly.

Chain

Resolution

2.7 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	I107 E116 V146
Catalytic site (residue number reindexed from 1)	I107 E116 V146
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	D37 E39 V60 L61 V62 G63 P64 R69 H70 M71 F72 V73 Q75	D37 E39 V60 L61 V62 G63 P64 R69 H70 M71 F72 V73 Q75
BS02	peptide	A	Y19 S133	Y19 S133

Gene Ontology

	Biological Process
GO:0006325	chromatin organization

	Cellular Component
GO:0005634	nucleus

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:2i32, PDBe:2i32, PDBj:2i32
PDBsum	2i32
PubMed	16980972
UniProt	Q9Y294\|ASF1A_HUMAN Histone chaperone ASF1A (Gene Name=ASF1A)

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