BioLiP

Structure of PDB 1ffp Chain A

Receptor sequence

>1ffpA (length=273) Species: 10090 (Mus musculus) [Search protein sequence]

PHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPW
MEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGC
DLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSG
AAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTL
RCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPL
GKEQNYTCRVYHEGLPEPLTLRW

3D structure

PDB

1ffp Peptidic termini play a significant role in TCR recognition

Chain

Resolution

2.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Y7 E63 K66 Q70 W73 S77 Y84 L95 Q97 T143 K146 W147 A152 H155 Y156 Y159 E163 W167 Y171	Y6 E62 K65 Q69 W72 S76 Y83 L94 Q96 T142 K145 W146 A151 H154 Y155 Y158 E162 W166 Y170

External links

PDB	RCSB:1ffp, PDBe:1ffp, PDBj:1ffp
PDBsum	1ffp
PubMed	12218131
UniProt	P01899\|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)

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