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Structure of PDB 8xgc Chain 6

Receptor sequence >8xgc6 (length=634) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] FKSRALNHVKKVDDVTGEKVREAFEQFLEDFSVQSTDTGEVEKVYRAQIE FMKIYDLNTIYIDYQHLSMRENGALAMAISEQYYRFLPFLQKGLRRVVRK YAPELLNTSSPEQTERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVT RTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWT LNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRC KFTGVEIVVPDVTQLGLPGVKPSLNSGVTGLRSLGVRDLTYKISFLACHV ISIGNERDQEVFLNSLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEA VKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFA PRSVYTSGKASSAAGLTAAVVRDDYTIEAGALMLADNGICCIDEFDKMDI SDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLSLR GNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKPPFSAEQLR RYIKYARTFKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVRQLES MIRLSEAIARANCVDEITPSFIAEAYDLLRQSII

3D structure PDB 8xgc Parental histone transfer caught at the replication fork. Chain 6 Resolution 3.7 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number 3.6.4.12: DNA helicase.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 dna 6 V612 K665 A666 V420 K469 A470 BS02 ADP 6 V797 R798 E801 V595 R596 E599 BS03 ZN 6 C311 C338 C166 C193 BS04 ADP 6 V537 F538 P577 S578 T579 S580 K581 S582 Q583 L727 V345 F346 P385 S386 T387 S388 K389 S390 Q391 L531

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003678 DNA helicase activity GO:0003688 DNA replication origin binding GO:0003697 single-stranded DNA binding GO:0004386 helicase activity GO:0005515 protein binding GO:0005524 ATP binding GO:0008270 zinc ion binding GO:0009378 four-way junction helicase activity GO:0016787 hydrolase activity GO:0016887 ATP hydrolysis activity GO:0017116 single-stranded DNA helicase activity GO:0043138 3'-5' DNA helicase activity GO:1990518 single-stranded 3'-5' DNA helicase activity

	Biological Process
GO:0000727	double-strand break repair via break-induced replication
GO:0006260	DNA replication
GO:0006267	pre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0006268	DNA unwinding involved in DNA replication
GO:0006270	DNA replication initiation
GO:0006271	DNA strand elongation involved in DNA replication
GO:0006279	premeiotic DNA replication
GO:0032508	DNA duplex unwinding
GO:1902969	mitotic DNA replication

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005656	nuclear pre-replicative complex
GO:0005737	cytoplasm
GO:0031261	DNA replication preinitiation complex
GO:0031298	replication fork protection complex
GO:0042555	MCM complex
GO:0043596	nuclear replication fork
GO:0071162	CMG complex
GO:0097373	MCM core complex

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