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Structure of PDB 6jum Chain A Binding Site BS03

Receptor Information >6jum Chain A (length=347) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] MTKWVLHVDLDQFLASVELRRRPDLRGQPVIVGGSGDPSEPRKVVTTASY EAREFGVHAGMPLRAAARRCPDATFLPSDPAAYDEASEQVMGLLRDLGHP LEVWGWDEAYLGADLPDESDPVEVAERIRTVVAAETGLSCSVGISDNKQR AKVATGFAKPAGIYVLTEANWMTVMGDRPPDALWGVGPKTTKKLAAMGIT TVADLAVTDPSVLTTAFGPSTGLWLLLLAKGGGDTEVSSEPWVPRSRSHV VTFPQDLTERREMDSAVRDLALQTLAEIVEQGRIVTRVAVTVRTSTFYTR TKIRKLPAPSTDAGQIVDTALAVLDQFELDRPVRLLGVRLELAMDDV

Ligand information >6jum Chain B (length=13) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] ctggggtcctagg

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6jum A polar filter in DNA polymerases prevents ribonucleotide incorporation. Resolution 1.78 Å Binding residue (original residue number in PDB) R42 V44 W242 R245 S246 R247 S248 H249 V250 T252 F297 R334 Binding residue (residue number reindexed from 1) R42 V44 W242 R245 S246 R247 S248 H249 V250 T252 F297 R334

Enzymatic activity Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.

Gene Ontology Molecular Function GO:0000287 magnesium ion binding GO:0003677 DNA binding GO:0003684 damaged DNA binding GO:0003887 DNA-directed DNA polymerase activity GO:0046872 metal ion binding

	Biological Process
GO:0006260	DNA replication
GO:0006261	DNA-templated DNA replication
GO:0006281	DNA repair
GO:0006974	DNA damage response
GO:0009432	SOS response
GO:0042276	error-prone translesion synthesis

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol

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