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BioLiP

Structure of PDB 8esr Chain F Binding Site BS02

Receptor Information
>8esr Chain F (length=214) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAEKKSARQKKRELIAKRAEAYEAEYRAAEREQIELARKARAEGNYFVPH
EPKLIFVVRIRGINNIPPKARKIMQLLRLLQINNGIFVKFNKAIKEMLQV
VEPYVTYGIPNHKTVRELIYKRGFGKVNKQRIPLSDNAIIEAALGKYSIL
SVEDLIHEIYTVGPNFKQAANFLWPFKLSSPLGGWRERKFKHFIEGGDAG
KRDEHINGLVQKML
Ligand information
>8esr Chain T (length=18) Species: 4896 (Schizosaccharomyces pombe) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AHFVSTENNEPVTLHPVA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8esr Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
L72 K75 A76 G80 N81 Y82 F83 V84 H86
Binding residue
(residue number reindexed from 1)
L36 K39 A40 G44 N45 Y46 F47 V48 H50
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8esr, PDBe:8esr, PDBj:8esr
PDBsum8esr
PubMed36423630
UniProtP25457|RL7B_SCHPO Large ribosomal subunit protein uL30B (Gene Name=rpl702)

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