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BioLiP

Structure of PDB 9bdc Chain E Binding Site BS02

Receptor Information
>9bdc Chain E (length=990) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVML
GWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIERC
LEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVN
TSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEK
PTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYP
FLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRV
SGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEALGAPEALREQPWPL
PVQMELGKLLAEMLVQATQMPCSLDKPHRSSRLVPVLYHVYSFRNVQQIG
ILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTK
LMRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQ
LFQAKGCPQLGVPAPPSEAPQPPEAHLPHSAAPARKAELRRELAHCQKVA
REMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSD
VARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMD
DILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPV
HQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQ
DAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSD
FPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVE
WVTPLGVPVIQPYRLDSRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCY
RKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKR
FCSEPQKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9bdc Structural basis for substrate binding and selection by human mitochondrial RNA polymerase.
Resolution2.54 Å
Binding residue
(original residue number in PDB)		N614 R805 G817 R822 M995 H1150
Binding residue
(residue number reindexed from 1)		N395 R586 G598 R603 M776 H910
External links
PDB RCSB:9bdc, PDBe:9bdc, PDBj:9bdc
PDBsum9bdc
PubMed39164235
UniProtO00411|RPOM_HUMAN DNA-directed RNA polymerase, mitochondrial (Gene Name=POLRMT)

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