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Structure of PDB 8qbd Chain C Binding Site BS02

Receptor Information >8qbd Chain C (length=271) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] MHRTYSLRNSRAPTASQLQNPPPPPSTTKGRFFGKGGLAYSFRRSAAGAF GPELSRKLSQLVKIEKNVLRSMELTANERRDAAKQLSIWGLENDDDVSDI TDKLGVLIYEVSELDDQFIDRYDQYRLTLKSIRDIEGSVQPSRDRKDKIT DKIAYLKYKDPQSPKIEVLEQELVRAEAESLVAEAQLSNITRSKLRAAFN YQFDSIIEHSEKIALIAGYGKALLELLDDSPVTPGETRPAYDGYEASKQI IIDAESALNEWTLDSAQVKPT

Ligand information Ligand ID P5S InChI InChI=1S/C42H82NO10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49)/t38-,39+/m1/s1 InChIKey TZCPCKNHXULUIY-RGULYWFUSA-N SMILES Software SMILES CACTVS 3.370 CCCCCCCCCCCCCCCCCC(=O)OC[CH](CO[P](O)(=O)OC[CH](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC CACTVS 3.370 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO[P](O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC ACDLabs 12.01 O=C(OC(COP(=O)(OCC(C(=O)O)N)O)COC(=O)CCCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCCC OpenEye OEToolkits 1.7.6 CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC(C(=O)O)N)OC(=O)CCCCCCCCCCCCCCCCC OpenEye OEToolkits 1.7.6 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OC[C@@H](C(=O)O)N)OC(=O)CCCCCCCCCCCCCCCCC Formula C42 H82 N O10 P Name O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine; phosphatidyl serine ChEMBL CHEMBL4297669 DrugBank DB00144 ZINC ZINC000085588270 PDB chain 8qbd Chain C Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8qbd Real-space refinement in PHENIX for cryo-EM and crystallography. Resolution 3.61 Å Binding residue (original residue number in PDB) A39 R43 K63 K66 R70 Binding residue (residue number reindexed from 1) A39 R43 K63 K66 R70 Annotation score 4

Gene Ontology Molecular Function GO:0005515 protein binding GO:0008289 lipid binding

	Biological Process
GO:0006897	endocytosis
GO:0008104	protein localization
GO:0070941	eisosome assembly
GO:0097446	protein localization to eisosome filament

	Cellular Component
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0005811	lipid droplet
GO:0005886	plasma membrane
GO:0032126	eisosome
GO:0036286	eisosome filament
GO:0071944	cell periphery

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