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BioLiP

Structure of PDB 8f0a Chain C Binding Site BS02

Receptor Information
>8f0a Chain C (length=302) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPSLAPMLEKVMPSVVSINVEGSTQKFMALGSGVIIDADKGYVVTNNHVV
DNATVIKVQLSDGRKFDAKMVGKDPRSDIALIQIQNPKNLTAIKMADSDA
LRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNAENYENFIQTDAAINR
GNAGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNLTSQMVEY
GQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAG
DVITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQS
SQ
Ligand information
>8f0a Chain c (length=27) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SKILLHYKFNNRTSVMLKDRWRTMKKL
Receptor-Ligand Complex Structure
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PDB8f0a Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		M85 A86 L87 H105 L190 N206 R207 G208 A210 A227 I228 A230
Binding residue
(residue number reindexed from 1)		M28 A29 L30 H48 L133 N149 R150 G151 A153 A170 I171 A173
Enzymatic activity
Enzyme Commision number 3.4.21.107: peptidase Do.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8f0a, PDBe:8f0a, PDBj:8f0a
PDBsum8f0a
PubMed37282495
UniProtP0C0V0|DEGP_ECOLI Periplasmic serine endoprotease DegP (Gene Name=degP)

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