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BioLiP

Structure of PDB 1z1g Chain C Binding Site BS02

Receptor Information
>1z1g Chain C (length=349) Species: 10710 (Lambdavirus lambda) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELFS
GHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAI
RRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAE
GHITTNHVAATRAAKSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAV
VTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTALHIDALGISMKE
TLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSFEGDPPTF
HELRSLSARLYEKQISDKFAQHLLGHKSDTMASQFRDDRGREWDKIEIK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1z1g A structural basis for allosteric control of DNA recombination by lambda integrase.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		K93 K95 T96 N99 Y100 K172 G214 S234 K235 S286 R287 M290 R293 T306 F307 H308
Binding residue
(residue number reindexed from 1)		K86 K88 T89 N92 Y93 K165 G207 S227 K228 S279 R280 M283 R286 T299 F300 H301
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008907 integrase activity
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0032359 provirus excision
GO:0044826 viral genome integration into host DNA
GO:0046718 symbiont entry into host cell
GO:0075713 establishment of integrated proviral latency

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Molecular Function
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Biological Process
External links
PDB RCSB:1z1g, PDBe:1z1g, PDBj:1z1g
PDBsum1z1g
PubMed15973401
UniProtP03700|VINT_LAMBD Integrase (Gene Name=int)

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