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Structure of PDB 8phe Chain A Binding Site BS02

Receptor Information >8phe Chain A (length=551) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] AFAKELFLGKIKKKEVFPFPEVSQDELNEINQFLGPVEKFFTEEVDSRKI DQEGKIPDETLEKLKSLGLFGLQVPEEYGGLGFSNTMYSRLGEIISMDGS ITVTLAAHQAIGLKGIILAGTEEQKAKYLPKLASGEHIAAFCLTEPASGS DAASIRSRATLSEDKKHYILNGSKVWITNGGLANIFTVFAKTEVVDSDGS VKDKITAFIVERDFGGVTNGKPEDKLGIRGSNTCEVHFENTKIPVENILG EVGDGFKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEYACTRKQFNKRLS EFGLIQEKFALMAQKAYVMESMTYLTAGMLDQPGFPDCSIEAAMVKVFSS EAAWQCVSEALQILGGLGYTRDYPYERILRDTRILLIFEGTNEILRMYIA LTGLQHAGRILTTRIHHGVVHPSLADSANKFEENTYCFGRTVETLLLRFG KTIMEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANT FCVEAYLQNLFSLSQLDKYAPENLDEQIKKVSQQILEKRAYICAHPLDRT C

Ligand information >8phe Chain D (length=15) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] TPEEWNLYYPMQLDL

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8phe The assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination Resolution 3.1 Å Binding residue (original residue number in PDB) L180 D188 A190 S191 I192 K239 I242 F293 M297 I431 Y435 L438 Q442 K521 M524 Binding residue (residue number reindexed from 1) L143 D151 A153 S154 I155 K202 I205 F256 M260 I394 Y398 L401 Q405 K451 M454

Enzymatic activity Enzyme Commision number 1.3.8.-

Gene Ontology Molecular Function GO:0003995 acyl-CoA dehydrogenase activity GO:0004466 long-chain fatty acyl-CoA dehydrogenase activity GO:0005515 protein binding GO:0016491 oxidoreductase activity GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors GO:0050660 flavin adenine dinucleotide binding GO:0070991 medium-chain fatty acyl-CoA dehydrogenase activity

	Biological Process
GO:0001676	long-chain fatty acid metabolic process
GO:0032981	mitochondrial respiratory chain complex I assembly
GO:0051791	medium-chain fatty acid metabolic process

	Cellular Component
GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0030425	dendrite
GO:0031966	mitochondrial membrane

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