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BioLiP

Structure of PDB 5c9h Chain A Binding Site BS02

Receptor Information
>5c9h Chain A (length=245) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QYIYPEIQRSQIFYCNHMGREPGVFKSSFFNYYQSKNFSCQEERDLFLEF
TEKIVQNFHNINFNYLLKKFCKLPENYQSLKSQVKQIVKANQQSCENLFN
SLYDTEISYKQITNFLRQIIQNCVPNQLLGKKNFKVFLEKLYEFVQMKRF
ENQKVLDYICFMDVFDVEWFVDLKNQKFTQKRKYISDKRKILGDLIVFII
NKIVIPVLRYNFYITEKHKEGSQIFYYRKPIWKLVSKLTIVKLEE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5c9h Structural basis of template-boundary definition in Tetrahymena telomerase.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		M235 R237 N324 K328 K332 L333 Y337 Q338 K341 R492 P494 K497
Binding residue
(residue number reindexed from 1)		M18 R20 N64 K68 K72 L73 Y77 Q78 K81 R228 P230 K233
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003964 RNA-directed DNA polymerase activity

View graph for
Molecular Function
External links
PDB RCSB:5c9h, PDBe:5c9h, PDBj:5c9h
PDBsum5c9h
PubMed26436828
UniProtO77448|TERT_TETTS Telomerase reverse transcriptase (Gene Name=TERT)

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