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Structure of PDB 4wrn Chain A Binding Site BS02

Receptor Information >4wrn Chain A (length=693) Species: 9606,83334 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] GHHHHHHKTEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKL EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFT WDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKG KSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLT FLVDLIKNKHMNADTDYSIAEHAFNHGETAMTINGPWAWSNIDTSAVNYG VTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAV NKDKPLGAVALKSYEEELVKDPRVAATMENAQKGEIMPNIPQMSAFWYAV RTAVINAASGRQTVDAALAAAQTNAAAGTCEECSIDEDCKSNNGRWHCQC KQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRCS GFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDL NIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPS YTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSQATDP LKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCE VYLCDTMNEKCKPTCSGTAFASGSVIDQSRVLNLGPITRKGVQ

Ligand information Ligand ID GLC InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1 InChIKey WQZGKKKJIJFFOK-DVKNGEFBSA-N SMILES Software SMILES OpenEye OEToolkits 1.5.0 C(C1C(C(C(C(O1)O)O)O)O)O OpenEye OEToolkits 1.5.0 C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O CACTVS 3.341 OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O CACTVS 3.341 OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O ACDLabs 10.04 OC1C(O)C(OC(O)C1O)CO Formula C6 H12 O6 Name alpha-D-glucopyranose; alpha-D-glucose; D-glucose; glucose ChEMBL CHEMBL423707 DrugBank ZINC ZINC000003861213 PDB chain 4wrn Chain C Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 4wrn A structured interdomain linker directs self-polymerization of human uromodulin. Resolution 3.2 Å Binding residue (original residue number in PDB) W86 D89 E177 P178 Y179 W364 Binding residue (residue number reindexed from 1) W69 D72 E160 P161 Y162 W347 Annotation score 4

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0015144 carbohydrate transmembrane transporter activity GO:1901982 maltose binding

	Biological Process
GO:0008643	carbohydrate transport
GO:0015768	maltose transport
GO:0034219	carbohydrate transmembrane transport
GO:0042956	maltodextrin transmembrane transport
GO:0055085	transmembrane transport

	Cellular Component
GO:0030288	outer membrane-bounded periplasmic space
GO:0042597	periplasmic space
GO:0055052	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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