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Structure of PDB 3k9f Chain A Binding Site BS02

Receptor Information >3k9f Chain A (length=481) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] NIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDS NTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEP TVLPAAFPNLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKID KLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKE QIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIEL KKDANTELVLNYLFKYTDLQINYNFNMVAIDNFTPRQVGIVPILSSYIAH RREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAK ENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAI IGDERTMYNLMKKELREVKKKFATPRLSSLE

Ligand information >3k9f Chain F (length=11) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] agtcattcatg

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 3k9f Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases Resolution 2.9 Å Binding residue (original residue number in PDB) Y118 I170 S171 G173 Y174 N326 Binding residue (residue number reindexed from 1) Y116 I168 S169 G171 Y172 N324

Enzymatic activity Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity GO:0005524 ATP binding

	Biological Process
GO:0006259	DNA metabolic process
GO:0006265	DNA topological change

	Cellular Component
GO:0005694	chromosome

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