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Structure of PDB 8rbz Chain c Binding Site BS01

Receptor Information >8rbz Chain c (length=463) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] RLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGLP QHEEICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKY LKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLA ESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQALRQKEVD FCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQ FTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQR QYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTS NVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLL DFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKE LRAMLREKFPEFC

Ligand information >8rbz Chain Y (length=13) Species: 9823 (Sus scrofa) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] SPSYSPTSPSYSP

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8rbz Structural basis of Integrator-dependent RNA polymerase II termination Resolution 3.7 Å Binding residue (original residue number in PDB) C80 K81 Binding residue (residue number reindexed from 1) C46 K47

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0005515 protein binding

	Biological Process
GO:0000724	double-strand break repair via homologous recombination
GO:0006281	DNA repair
GO:0006974	DNA damage response
GO:0010212	response to ionizing radiation
GO:0016180	snRNA processing
GO:0034243	regulation of transcription elongation by RNA polymerase II
GO:0044818	mitotic G2/M transition checkpoint

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0032039	integrator complex
GO:0035861	site of double-strand break
GO:0070876	SOSS complex

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